Treatment Adherence – One of the Most Challenging Issues in Global Health

South Africa, Johannesburg, March 5, 2025 – /AMA/ – First World Compliance Day launched on March 27, 2025 is a call for health care professionals and patients to adhere to treatment plans, one of the most challenging issues in global health.
This year’s campaign, #DontMissamoment, addressed widespread non-compliance, which led to worsening health outcomes, unnecessary hospitalizations and rising health care costs. The World Heart Federation (WHF) leads rally support from the global scientific and medical societies to endorse this initiative.
The purpose of this activity is:
- educate Patients, caregivers and healthcare professionals about compliance.
- encourage There is a public conversation between doctors and patients about treatment plans.
- Engaged Community through workshops, social media campaigns and public outreach activities.
- promote Policy for improving access to drugs and adherence support systems.

Need better compliance
The global death toll is about 75% of deaths1at least 43 million per year. In South Africa, the prevalence of NCD has been increasing significantly. Between 1997 and 2018, major NCD deaths, including cardiovascular disease, cancer, diabetes and chronic lower respiratory tract disease, increased by 58.7%.2 Hypertension is very common, with the number of people in South Africa as of 2019 at about 4.74 million.3 In addition, 17.8% of the population suffer from HIV/AIDS.4
Adherence – Adhere to prescription medications, lifestyle changes and regular medical visits – is critical to managing chronic conditions such as hypertension, diabetes and cardiovascular disease. Poor compliance increases mortality and medical expenses. However, only 50% of patients in high-income countries adhere to chronic disease treatment, and the incidence rate is even lower in developing countries.5
“This leads to preventable complications, hospitalization and millions of quality of life worldwide,” said Virosha Deonarain, head of medical affairs at Pharmaceuticals, Southern and East African Services. “Improving compliance could significantly reduce the risk of long-term mortality.”
Healthcare providers must lead
Despite life-saving treatments, many patients are still struggling to maintain compliance due to lack of awareness, treatment fatigue, financial disorders and misunderstandings about side effects of medications.
When health care providers actively interact with patients, they can significantly improve medication adherence. It is important that doctors, nurses and pharmacists ask the right questions to patients to help promote compliance, which is important.
Improving adherence can improve patient outcomes and reduce long-term health care costs. In addition to patient education, health care providers play a vital role in advocating policies to improve access to essential medicines, ensuring better health equity and continuity of care.
Authorized patients to control health
Patients who actively manage their treatment plans experience better health outcomes and fewer complications. To improve compliance, patients should ask the following questions:
- What is the purpose of this drug? How did it help me?
- What specific changes should I make to my diet, activity level, or daily habits?
- How do these changes support my treatment plan?
- How often should I schedule a follow-up date?
- What if I forget to take the medicine?
“If we all work together, we can make sure compliance is a shared responsibility, not a burden,” said Dr. Martin MPE, president of the SA Heart Association. “By taking action today, health care professionals and patients can ensure that no one misses any moment due to preventable health issues.”
Show your support to World Compliance Day 2025 by committing to better treatment compliance. #dontmissamoment
Follow the activities:
Depend on African Media Organization (AMA) Representative Service
About the service provider:
As people who serve, we are committed to providing treatment progress to patient needs with the help of healthcare professionals. We strive to provide a world of quality health care for future generations.
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Kerry Simpson
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